BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM50222875'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Ovis aries)	BDBM50222875 (6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidi...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay				J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50222875 (6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Agonist activity at human recombinant GHSR1a expressed in HEK293F cells assessed as stimulation of [35S]GTP-gamma-S binding relative to ghrelin				J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair