Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM213326'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM213326 (US9278968, 82) Show SMILES Cc1nc2c(OCc3cccc(F)c3F)cccn2c1C(=O)NC(C)(CO)c1nnn(C)n1 Show InChI InChI=1S/C21H21F2N7O3/c1-12-17(19(32)25-21(2,11-31)20-26-28-29(3)27-20)30-9-5-8-15(18(30)24-12)33-10-13-6-4-7-14(22)16(13)23/h4-9,31H,10-11H2,1-3H3,(H,25,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description Using an sGCα 1 gene (NCBI accession No. BC028384.2) and an sGCβ1 gene (NCBI accession No. BC047620.1), an N-terminal FLAG tag-fused sGC&a...				US Patent US9278968 (2016) BindingDB Entry DOI: 10.7270/Q2T43RXS
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