Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM213345'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM213345 (US9278968, 101) Show SMILES CCn1cc(cn1)C(CO)(CO)NC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12 Show InChI InChI=1S/C24H25F2N5O4/c1-3-30-11-16(10-27-30)24(13-32,14-33)29-23(34)21-15(2)28-22-20(8-5-9-31(21)22)35-12-17-18(25)6-4-7-19(17)26/h4-11,32-33H,3,12-14H2,1-2H3,(H,29,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description Using an sGCα 1 gene (NCBI accession No. BC028384.2) and an sGCβ1 gene (NCBI accession No. BC047620.1), an N-terminal FLAG tag-fused sGC&a...				US Patent US9278968 (2016) BindingDB Entry DOI: 10.7270/Q2T43RXS
					More data for this Ligand-Target Pair