Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM213347'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM213347 (US9278968, 103) Show SMILES Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1nnn(CC2CC2)n1 Show InChI InChI=1S/C24H25F2N7O3/c1-14-20(22(35)28-24(2,13-34)23-29-31-33(30-23)11-15-8-9-15)32-10-4-7-19(21(32)27-14)36-12-16-17(25)5-3-6-18(16)26/h3-7,10,15,34H,8-9,11-13H2,1-2H3,(H,28,35)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description Using an sGCα 1 gene (NCBI accession No. BC028384.2) and an sGCβ1 gene (NCBI accession No. BC047620.1), an N-terminal FLAG tag-fused sGC&a...				US Patent US9278968 (2016) BindingDB Entry DOI: 10.7270/Q2T43RXS
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