Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM213363'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM213363 (US9278968, 117) Show SMILES Cc1nnc(o1)[C@](C)(CO)NC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12 |r| Show InChI InChI=1S/C22H21F2N5O4/c1-12-18(20(31)26-22(3,11-30)21-28-27-13(2)33-21)29-9-5-8-17(19(29)25-12)32-10-14-15(23)6-4-7-16(14)24/h4-9,30H,10-11H2,1-3H3,(H,26,31)/t22-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description Using an sGCα 1 gene (NCBI accession No. BC028384.2) and an sGCβ1 gene (NCBI accession No. BC047620.1), an N-terminal FLAG tag-fused sGC&a...				US Patent US9278968 (2016) BindingDB Entry DOI: 10.7270/Q2T43RXS
					More data for this Ligand-Target Pair