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Found 1 hit Enz. Inhib. hit(s) with Target = 'HTH-type transcriptional regulator EthR' and Ligand = 'BDBM50363025'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTH-type transcriptional regulator EthR


(Mycobacterium tuberculosis)		BDBM50363025
PNG
(CHEMBL1945820)
Show SMILES Fc1cccc(c1)-c1noc(n1)C1CCN(CC1)C(=O)CCC(F)(F)F
Show InChI InChI=1S/C17H17F4N3O2/c18-13-3-1-2-12(10-13)15-22-16(26-23-15)11-5-8-24(9-6-11)14(25)4-7-17(19,20)21/h1-3,10-11H,4-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



Universit£ Lille Nord de France

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis H37Rv EthR in Mycobacterium tuberculosis H37Rv expressing GFP infected mouse in RAW264.7 cells assessed as p...

J Med Chem 55: 68-83 (2012)


Article DOI: 10.1021/jm200825u
BindingDB Entry DOI: 10.7270/Q2RX9CJW
More data for this
Ligand-Target Pair