Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM120815'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120815 ((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCCC1 |w:14.14| Show InChI InChI=1S/C35H33F4N5O4/c1-22-25(34(45)44(42-22)29-9-4-3-8-26(29)35(37,38)39)21-41-23-10-11-31(27(36)18-23)48-30-12-13-40-28-20-33(32(46-2)19-24(28)30)47-17-7-16-43-14-5-6-15-43/h3-4,8-13,18-21,42H,5-7,14-17H2,1-2H3/b41-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.04	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
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