Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM120817'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120817 ((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCCCC1 |w:14.14| Show InChI InChI=1S/C36H35F4N5O4/c1-23-26(35(46)45(43-23)30-10-5-4-9-27(30)36(38,39)40)22-42-24-11-12-32(28(37)19-24)49-31-13-14-41-29-21-34(33(47-2)20-25(29)31)48-18-8-17-44-15-6-3-7-16-44/h4-5,9-14,19-22,43H,3,6-8,15-18H2,1-2H3/b42-22+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.63	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
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