Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM259936'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259936 (US9512121, 14) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5OCCCOc5c4c3)n2c1 Show InChI InChI=1S/C22H17FN6O2S/c1-28-11-14(9-25-28)13-7-17(23)21-26-27-22(29(21)12-13)32-15-3-4-18-16(8-15)20-19(10-24-18)30-5-2-6-31-20/h3-4,7-12H,2,5-6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
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