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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50023340'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50023340
PNG
(CHEMBL3334565)
Show SMILES Fc1ccc(cc1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
Show InChI InChI=1S/C18H12FN7/c19-14-4-2-13(3-5-14)15-9-21-17-18(22-15)26(24-23-17)11-12-1-6-16-20-7-8-25(16)10-12/h1-10H,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Hutchison MediPharma Limited

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay


J Med Chem 57: 7577-89 (2014)


Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50023340
PNG
(CHEMBL3334565)
Show SMILES Fc1ccc(cc1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
Show InChI InChI=1S/C18H12FN7/c19-14-4-2-13(3-5-14)15-9-21-17-18(22-15)26(24-23-17)11-12-1-6-16-20-7-8-25(16)10-12/h1-10H,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Hutchison MediPharma Limited

Curated by ChEMBL


Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA


J Med Chem 57: 7577-89 (2014)


Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR
More data for this
Ligand-Target Pair