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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50103916'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50103916
PNG
(CHEMBL3593882)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Br)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C37H39BrFN5O5/c1-23-13-17-43(18-14-23)16-5-19-48-34-22-30-28(21-33(34)47-4)31(12-15-40-30)49-32-11-8-26(20-29(32)39)41-36(45)35-24(2)44(37(46)42(35)3)27-9-6-25(38)7-10-27/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,41,45)
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Article
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n/an/a 18n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 23: 4410-22 (2015)


Article DOI: 10.1016/j.bmc.2015.06.026
BindingDB Entry DOI: 10.7270/Q28G8NG3
More data for this
Ligand-Target Pair