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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50103922'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50103922
PNG
(CHEMBL3593686)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(C)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C37H41FN6O5/c1-24-7-10-27(11-8-24)44-25(2)35(42(4)37(44)46)36(45)40-26-9-12-32(29(38)21-26)49-31-13-14-39-30-23-34(33(47-5)22-28(30)31)48-20-6-15-43-18-16-41(3)17-19-43/h7-14,21-23H,6,15-20H2,1-5H3,(H,40,45)
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Article
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n/an/a 24n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 23: 4410-22 (2015)


Article DOI: 10.1016/j.bmc.2015.06.026
BindingDB Entry DOI: 10.7270/Q28G8NG3
More data for this
Ligand-Target Pair