Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50248089'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248089 (CHEMBL517469 | N-(4-(2-(1-ethyl-1H-imidazol-4-yl)t...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C28H22F2N6O3S/c1-2-34-15-21(32-16-34)25-14-20-26(40-25)24(9-10-31-20)39-23-8-7-17(13-19(23)30)33-27(37)36-12-11-35(28(36)38)22-6-4-3-5-18(22)29/h3-10,13-16H,2,11-12H2,1H3,(H,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant c-Met (unknown origin) catalytic domain expressed in baculovirus-infected Trichoplusia ni Hi5 cells after 30 mins...				Bioorg Med Chem Lett 19: 1323-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.068 BindingDB Entry DOI: 10.7270/Q23F4PHJ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248089 (CHEMBL517469 | N-(4-(2-(1-ethyl-1H-imidazol-4-yl)t...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C28H22F2N6O3S/c1-2-34-15-21(32-16-34)25-14-20-26(40-25)24(9-10-31-20)39-23-8-7-17(13-19(23)30)33-27(37)36-12-11-35(28(36)38)22-6-4-3-5-18(22)29/h3-10,13-16H,2,11-12H2,1H3,(H,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248089 (CHEMBL517469 | N-(4-(2-(1-ethyl-1H-imidazol-4-yl)t...) Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4F)cc3F)c2s1 Show InChI InChI=1S/C28H22F2N6O3S/c1-2-34-15-21(32-16-34)25-14-20-26(40-25)24(9-10-31-20)39-23-8-7-17(13-19(23)30)33-27(37)36-12-11-35(28(36)38)22-6-4-3-5-18(22)29/h3-10,13-16H,2,11-12H2,1H3,(H,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of TPR-fused Met (unknown origin) phosphorylation expressed in human 293T cells by ELISA				Bioorg Med Chem Lett 19: 1323-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.068 BindingDB Entry DOI: 10.7270/Q23F4PHJ
					More data for this Ligand-Target Pair