BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50269504'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50269504
PNG
(CHEMBL4098250)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nc5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C40H37F2N5O5/c1-25-15-19-46(20-16-25)18-5-21-51-37-24-32-29(23-36(37)50-2)34(14-17-43-32)52-35-13-10-27(22-30(35)42)44-39(48)38-40(49)47(28-11-8-26(41)9-12-28)33-7-4-3-6-31(33)45-38/h3-4,6-14,17,22-25H,5,15-16,18-21H2,1-2H3,(H,44,48)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China; College of Pharma

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 25: 4475-4486 (2017)


Article DOI: 10.1016/j.bmc.2017.06.037
BindingDB Entry DOI: 10.7270/Q2PC34W2
More data for this
Ligand-Target Pair