Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50334084 (2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc Curated by ChEMBL | Assay Description Inhibition of human c-Met in human GTL16 cells by cell-based assay | Bioorg Med Chem Lett 21: 164-7 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.045 BindingDB Entry DOI: 10.7270/Q28W3F85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50334084 (2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay | Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50334084 (2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc Curated by ChEMBL | Assay Description Inhibition of c-Met | Bioorg Med Chem Lett 21: 164-7 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.045 BindingDB Entry DOI: 10.7270/Q28W3F85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50334084 (2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay | Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J | |||||||||||
More data for this Ligand-Target Pair |