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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50361567'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50361567
PNG
(CHEMBL1939494)
Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@H](CC3(C)C)NC(=O)OC)c2)ncc1Cl |r|
Show InChI InChI=1S/C26H27ClFN7O4/c1-26(2)11-19(33-25(38)39-4)23(37)32-18-10-13(8-9-15(18)26)31-24-30-12-16(27)21(35-24)34-20-14(22(36)29-3)6-5-7-17(20)28/h5-10,12,19H,11H2,1-4H3,(H,29,36)(H,32,37)(H,33,38)(H2,30,31,34,35)/t19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Cephalon, Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay


Bioorg Med Chem 19: 6274-84 (2011)


Article DOI: 10.1016/j.bmc.2011.09.006
BindingDB Entry DOI: 10.7270/Q24M950J
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50361567
PNG
(CHEMBL1939494)
Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@H](CC3(C)C)NC(=O)OC)c2)ncc1Cl |r|
Show InChI InChI=1S/C26H27ClFN7O4/c1-26(2)11-19(33-25(38)39-4)23(37)32-18-10-13(8-9-15(18)26)31-24-30-12-16(27)21(35-24)34-20-14(22(36)29-3)6-5-7-17(20)28/h5-10,12,19H,11H2,1-4H3,(H,29,36)(H,32,37)(H,33,38)(H2,30,31,34,35)/t19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Cephalon, Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay


Bioorg Med Chem 19: 6274-84 (2011)


Article DOI: 10.1016/j.bmc.2011.09.006
BindingDB Entry DOI: 10.7270/Q24M950J
More data for this
Ligand-Target Pair