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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50419119'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50419119
PNG
(CHEMBL1824607)
Show SMILES O=C(Nc1ccccc1)c1ccc(OCCCN2CCCC2)cc1OCc1cccc(c1)C#N
Show InChI InChI=1S/C28H29N3O3/c29-20-22-8-6-9-23(18-22)21-34-27-19-25(33-17-7-16-31-14-4-5-15-31)12-13-26(27)28(32)30-24-10-2-1-3-11-24/h1-3,6,8-13,18-19H,4-5,7,14-17,21H2,(H,30,32)
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PC cid
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Similars
Article
PubMed
n/an/a 617n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged wild type c-met kinase domain (residues 1056-1371) using biotin-poly EAY as substrate in the presence of ATP aft...

Bioorg Med Chem Lett 21: 5224-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.047
BindingDB Entry DOI: 10.7270/Q2K35VX8
More data for this
Ligand-Target Pair