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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50536473'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50536473
PNG
(CHEMBL4570217)
Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1 |r|
Show InChI InChI=1S/C23H16F2N6O/c1-12(16-7-13-3-2-6-27-19(13)9-18(16)25)31-11-29-22-23(31)30-20(10-28-22)14-4-5-15(21(26)32)17(24)8-14/h2-12H,1H3,(H2,26,32)/t12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.30n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...


Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
BindingDB Entry DOI: 10.7270/Q2PN9949
More data for this
Ligand-Target Pair