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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50536516'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50536516
PNG
(CHEMBL4554510)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2ncn(C(C)c3cc4cccnc4cc3F)c2n1
Show InChI InChI=1S/C24H18F2N6O/c1-13(17-8-14-4-3-7-28-20(14)10-19(17)26)32-12-30-22-23(32)31-21(11-29-22)15-5-6-16(18(25)9-15)24(33)27-2/h3-13H,1-2H3,(H,27,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.30n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...


Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
BindingDB Entry DOI: 10.7270/Q2PN9949
More data for this
Ligand-Target Pair