Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor [960-1390]' and Ligand = 'BDBM62337'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor [960-1390] (Homo sapiens (Human))	BDBM62337 (Synthetic Example 4 (WO2008/071451)) Show SMILES CC1=C(C#N)C(C(C#N)=C(C)N1)c1cccc2[nH]ncc12 |c:1,t:8| Show InChI InChI=1S/C16H13N5/c1-9-12(6-17)16(13(7-18)10(2)20-9)11-4-3-5-15-14(11)8-19-21-15/h3-5,8,16,20H,1-2H3,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The N-terminally His6-tagged recombinant kinase domain of the human c-Met (amino acids 960-1390), expressed in insect cells (SF21) and purified by Ni...				US Patent US9422263 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZW2
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