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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor [D1228H]' and Ligand = 'BDBM516964'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor [D1228H]


(Homo sapiens (Human))
BDBM516964
PNG
(N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...)
Show SMILES CC(Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12)C(C)(C)O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a


TBA

Assay Description
The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2BZ6962
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor [D1228H]


(Homo sapiens (Human))
BDBM516964
PNG
(N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...)
Show SMILES CC(Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12)C(C)(C)O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.80n/an/an/an/an/an/a


TBA

Assay Description
The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2BZ6962
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor [D1228H]


(Homo sapiens (Human))
BDBM516964
PNG
(N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...)
Show SMILES CC(Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12)C(C)(C)O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 52.8n/an/an/an/an/an/a


TBA

Assay Description
The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2BZ6962
More data for this
Ligand-Target Pair