Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A' and Ligand = 'BDBM140122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM140122 (US8901315, 238) Show SMILES Cc1nn(C2CCCCC2)c2sc(cc12)C(=O)NC1CC[C@@H](CC1)C(=O)NC1CC1 |r,wD:21.27,(-7.6,4.1,;-6.83,2.77,;-7.74,1.52,;-6.83,.27,;-7.23,-1.21,;-8.72,-1.61,;-9.12,-3.1,;-8.03,-4.19,;-6.54,-3.79,;-6.14,-2.3,;-5.37,.75,;-3.9,.27,;-3,1.52,;-3.9,2.77,;-5.37,2.29,;-1.46,1.52,;-.69,.19,;-.69,2.85,;.85,2.85,;1.62,4.19,;3.16,4.19,;3.93,2.85,;3.16,1.52,;1.62,1.52,;5.47,2.85,;6.24,4.19,;6.24,1.52,;7.78,1.52,;9.12,.75,;9.12,2.29,)| Show InChI InChI=1S/C23H32N4O2S/c1-14-19-13-20(30-23(19)27(26-14)18-5-3-2-4-6-18)22(29)25-16-9-7-15(8-10-16)21(28)24-17-11-12-17/h13,15-18H,2-12H2,1H3,(H,24,28)(H,25,29)/t15-,16?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	7.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
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