Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A' and Ligand = 'BDBM350892'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM350892 (3-(2-Bromophenyl)-2-cyclopropylmethylthio-4-oxo-3,...) Show SMILES Brc1ccccc1-n1c(SCC2CC2)nc2ccccc2c1=O |(1.33,-5.39,;,-4.62,;-1.33,-5.39,;-2.67,-4.62,;-2.67,-3.08,;-1.33,-2.31,;,-3.08,;1.33,-2.31,;1.33,-.77,;;-1.33,-.77,;-2.67,,;-4.21,,;-3.44,1.33,;2.67,,;4,-.77,;5.33,,;6.67,-.77,;6.67,-2.31,;5.33,-3.08,;4,-2.31,;2.67,-3.08,;2.67,-4.62,)| Show InChI InChI=1S/C18H15BrN2OS/c19-14-6-2-4-8-16(14)21-17(22)13-5-1-3-7-15(13)20-18(21)23-11-12-9-10-12/h1-8,12H,9-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS US Patent					Assay Description Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...				US Patent US9796687 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MDC
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