Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human)) | BDBM50151530 (3-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cells | Bioorg Med Chem Lett 14: 4607-13 (2004) Article DOI: 10.1016/j.bmcl.2004.07.008 BindingDB Entry DOI: 10.7270/Q2377855 | |||||||||||
More data for this Ligand-Target Pair |