Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM317099'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM317099 (US9617269, Compound WYQ-50) Show SMILES Clc1cccc(CNc2nc3n(ncc3c(=O)[nH]2)C2CCCCC2)c1 Show InChI InChI=1S/C18H20ClN5O/c19-13-6-4-5-12(9-13)10-20-18-22-16-15(17(25)23-18)11-21-24(16)14-7-2-1-3-8-14/h4-6,9,11,14H,1-3,7-8,10H2,(H2,20,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University; University of North Carolina at Chapel Hill US Patent					Assay Description Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...				US Patent US9617269 (2017) BindingDB Entry DOI: 10.7270/Q2RX9F4B
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