Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM50398793'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM50398793 (CHEMBL2177502) Show SMILES C[C@@H](N1CCCC(C1)c1cccc(C)c1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r| Show InChI InChI=1S/C24H31N5O/c1-16-7-5-8-18(13-16)19-9-6-12-28(15-19)17(2)22-26-23-21(24(30)27-22)14-25-29(23)20-10-3-4-11-20/h5,7-8,13-14,17,19-20H,3-4,6,9-12,15H2,1-2H3,(H,26,27,30)/t17-,19?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay				J Med Chem 55: 9055-68 (2012) Article DOI: 10.1021/jm3009635 BindingDB Entry DOI: 10.7270/Q2CR5VHK
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