Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM186353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM186353 (US9163021, 10) Show SMILES CC(C)(CO)n1cc(C(=O)c2cc(NC(=O)Cn3ccc(n3)C(F)(F)F)ccn2)c2cnccc12 Show InChI InChI=1S/C23H21F3N6O3/c1-22(2,13-33)32-11-16(15-10-27-6-4-18(15)32)21(35)17-9-14(3-7-28-17)29-20(34)12-31-8-5-19(30-31)23(24,25)26/h3-11,33H,12-13H2,1-2H3,(H,28,29,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...				US Patent US9163021 (2015) BindingDB Entry DOI: 10.7270/Q29C6W7C
					More data for this Ligand-Target Pair