Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM186433'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM186433 (US9163021, 91) Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(cn3)C3CC3)c2)c2cncc(F)c12 Show InChI InChI=1S/C24H23FN6O2/c1-14(2)31-12-20(19-9-27-10-21(25)23(19)31)24(33)16-5-18(8-26-6-16)29-22(32)13-30-11-17(7-28-30)15-3-4-15/h5-12,14-15H,3-4,13H2,1-2H3,(H,29,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...				US Patent US9163021 (2015) BindingDB Entry DOI: 10.7270/Q29C6W7C
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