Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM200636'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200636 (US10590139, Example 60 | US9227975, 60 | US9796723...) Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccc2ncc(NC(=O)C(F)(F)F)n2n1 |r| Show InChI InChI=1S/C18H14F5N5O/c19-10-3-4-12(20)11(8-10)13-2-1-7-27(13)15-6-5-14-24-9-16(28(14)26-15)25-17(29)18(21,22)23/h3-6,8-9,13H,1-2,7H2,(H,25,29)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9227975 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WKV
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200636 (US10590139, Example 60 | US9227975, 60 | US9796723...) Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccc2ncc(NC(=O)C(F)(F)F)n2n1 |r| Show InChI InChI=1S/C18H14F5N5O/c19-10-3-4-12(20)11(8-10)13-2-1-7-27(13)15-6-5-14-24-9-16(28(14)26-15)25-17(29)18(21,22)23/h3-6,8-9,13H,1-2,7H2,(H,25,29)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US10590139 (2020) BindingDB Entry DOI: 10.7270/Q21C20W4
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200636 (US10590139, Example 60 | US9227975, 60 | US9796723...) Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccc2ncc(NC(=O)C(F)(F)F)n2n1 |r| Show InChI InChI=1S/C18H14F5N5O/c19-10-3-4-12(20)11(8-10)13-2-1-7-27(13)15-6-5-14-24-9-16(28(14)26-15)25-17(29)18(21,22)23/h3-6,8-9,13H,1-2,7H2,(H,25,29)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9796723 (2017) BindingDB Entry DOI: 10.7270/Q2CC12SB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200636 (US10590139, Example 60 | US9227975, 60 | US9796723...) Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccc2ncc(NC(=O)C(F)(F)F)n2n1 |r| Show InChI InChI=1S/C18H14F5N5O/c19-10-3-4-12(20)11(8-10)13-2-1-7-27(13)15-6-5-14-24-9-16(28(14)26-15)25-17(29)18(21,22)23/h3-6,8-9,13H,1-2,7H2,(H,25,29)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9795611 (2017) BindingDB Entry DOI: 10.7270/Q25T3NMH
					More data for this Ligand-Target Pair