Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM356178'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM356178 (N-(5-(1-aminoethyl)-6'-phenyl- [2,3'-bipyridin]-5'...) Show SMILES CC(N)c1ccc(nc1)-c1cnc(c(NC(=O)c2cc(-c3ccn(C)n3)c(cc2F)C(F)(F)F)c1)-c1ccccc1 Show InChI InChI=1S/C30H24F4N6O/c1-17(35)19-8-9-25(36-15-19)20-12-27(28(37-16-20)18-6-4-3-5-7-18)38-29(41)22-13-21(26-10-11-40(2)39-26)23(14-24(22)31)30(32,33)34/h3-17H,35H2,1-2H3,(H,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...				US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R
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