Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM364525'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM364525 (US9862707, Example 100) Show SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1n(nc2cc(ccc12)[C@@H](N)C(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C27H20F6N6O/c1-38-12-11-21(36-38)19-13-16(8-10-20(19)26(28,29)30)25(40)35-24-18-9-7-15(23(34)27(31,32)33)14-22(18)37-39(24)17-5-3-2-4-6-17/h2-14,23H,34H2,1H3,(H,35,40)/t23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universitat Bonn					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...				J Med Chem 48: 7688-707 (2005) BindingDB Entry DOI: 10.7270/Q2FB5576
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