Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM373106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM373106 (1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-[4- (tr...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2c(nc3ccccn23)-c2ccccc2)cc1 Show InChI InChI=1S/C21H15F3N4O/c22-21(23,24)15-9-11-16(12-10-15)25-20(29)27-19-18(14-6-2-1-3-7-14)26-17-8-4-5-13-28(17)19/h1-13H,(H2,25,27,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...				J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH
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