Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM373116'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM373116 (1-(1-methyl-4- phenyl-1H-imidazol- 5-yl)-3-(2-meth...) Show SMILES Cc1nc(c(NC(=O)Nc2c(ncn2C)-c2ccccc2)s1)-c1ccccc1 Show InChI InChI=1S/C21H19N5OS/c1-14-23-18(16-11-7-4-8-12-16)20(28-14)25-21(27)24-19-17(22-13-26(19)2)15-9-5-3-6-10-15/h3-13H,1-2H3,(H2,24,25,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...				J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH
					More data for this Ligand-Target Pair