Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM376048'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM376048 (N-(1',4-dimethyl-1-phenyl- 1H,1'H-3,4'-bipyrazol-5...) Show SMILES Cc1c(NC(=O)c2ccc(c(c2)-c2ccn(C)n2)C(F)(F)F)n(nc1-c1cnn(C)c1)-c1ccccc1 Show InChI InChI=1S/C26H22F3N7O/c1-16-23(18-14-30-35(3)15-18)33-36(19-7-5-4-6-8-19)24(16)31-25(37)17-9-10-21(26(27,28)29)20(13-17)22-11-12-34(2)32-22/h4-15H,1-3H3,(H,31,37)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur					Assay Description In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...				J Med Chem 51: 3077-80 (2008) BindingDB Entry DOI: 10.7270/Q2WQ0629
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