Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM376050'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM376050 (2-chloro-N-(4-methyl-1- phenyl-1H-pyrazol-5-yl)-5-...) Show SMILES Cc1cnn(c1NC(=O)c1cc(-c2ccn(C)n2)c(cc1Cl)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C22H17ClF3N5O/c1-13-12-27-31(14-6-4-3-5-7-14)20(13)28-21(32)16-10-15(19-8-9-30(2)29-19)17(11-18(16)23)22(24,25)26/h3-12H,1-2H3,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur					Assay Description In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...				J Med Chem 51: 3077-80 (2008) BindingDB Entry DOI: 10.7270/Q2WQ0629
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