Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM376073'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM376073 (3-(1-methyl-1H-pyrazol-3-yl)- N-[5'-methyl-3-(pyrr...) Show SMILES Cc1cc([nH]n1)-n1nc(CN2CCCC2)cc1NC(=O)c1ccc(c(c1)-c1ccn(C)n1)C(F)(F)F Show InChI InChI=1S/C24H25F3N8O/c1-15-11-22(30-29-15)35-21(13-17(31-35)14-34-8-3-4-9-34)28-23(36)16-5-6-19(24(25,26)27)18(12-16)20-7-10-33(2)32-20/h5-7,10-13H,3-4,8-9,14H2,1-2H3,(H,28,36)(H,29,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur					Assay Description In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...				J Med Chem 51: 3077-80 (2008) BindingDB Entry DOI: 10.7270/Q2WQ0629
					More data for this Ligand-Target Pair