Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM412283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412283 (US10399945, Example 22 | US10669239, Compound 22 |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-10-9-17(26)12-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021) BindingDB Entry DOI: 10.7270/Q2988B3P
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412283 (US10399945, Example 22 | US10669239, Compound 22 |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-10-9-17(26)12-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412283 (US10399945, Example 22 | US10669239, Compound 22 |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-10-9-17(26)12-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair