Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM412307'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412307 (US10399945, Example 41a | US10669239, Compound 41a...) Show SMILES Cc1nnc(CNC(=O)c2nc(c(NC(=O)N[C@H]3[C@H](O)CC(C)(C)c4cc(F)c(F)cc34)cc2C)-c2ccccc2)o1 |r| Show InChI InChI=1S/C30H30F2N6O4/c1-15-10-22(34-29(41)36-27-18-11-20(31)21(32)12-19(18)30(3,4)13-23(27)39)26(17-8-6-5-7-9-17)35-25(15)28(40)33-14-24-38-37-16(2)42-24/h5-12,23,27,39H,13-14H2,1-4H3,(H,33,40)(H2,34,36,41)/t23-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021) BindingDB Entry DOI: 10.7270/Q2988B3P
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412307 (US10399945, Example 41a | US10669239, Compound 41a...) Show SMILES Cc1nnc(CNC(=O)c2nc(c(NC(=O)N[C@H]3[C@H](O)CC(C)(C)c4cc(F)c(F)cc34)cc2C)-c2ccccc2)o1 |r| Show InChI InChI=1S/C30H30F2N6O4/c1-15-10-22(34-29(41)36-27-18-11-20(31)21(32)12-19(18)30(3,4)13-23(27)39)26(17-8-6-5-7-9-17)35-25(15)28(40)33-14-24-38-37-16(2)42-24/h5-12,23,27,39H,13-14H2,1-4H3,(H,33,40)(H2,34,36,41)/t23-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412307 (US10399945, Example 41a | US10669239, Compound 41a...) Show SMILES Cc1nnc(CNC(=O)c2nc(c(NC(=O)N[C@H]3[C@H](O)CC(C)(C)c4cc(F)c(F)cc34)cc2C)-c2ccccc2)o1 |r| Show InChI InChI=1S/C30H30F2N6O4/c1-15-10-22(34-29(41)36-27-18-11-20(31)21(32)12-19(18)30(3,4)13-23(27)39)26(17-8-6-5-7-9-17)35-25(15)28(40)33-14-24-38-37-16(2)42-24/h5-12,23,27,39H,13-14H2,1-4H3,(H,33,40)(H2,34,36,41)/t23-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair