Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50502894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50502894 (CHEMBL4458775) Show SMILES Cc1ccn2c(c1)nc(CSc1nnc(NC(=O)Nc3ccc(C)c(Cl)c3)s1)cc2=O Show InChI InChI=1S/C20H17ClN6O2S2/c1-11-5-6-27-16(7-11)22-14(9-17(27)28)10-30-20-26-25-19(31-20)24-18(29)23-13-4-3-12(2)15(21)8-13/h3-9H,10H2,1-2H3,(H2,23,24,25,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Zoetis Inc Curated by ChEMBL					Assay Description Inhibition of His-tagged recombinant human ATP-activated TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system preincub...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126680 BindingDB Entry DOI: 10.7270/Q2280BVB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50502894 (CHEMBL4458775) Show SMILES Cc1ccn2c(c1)nc(CSc1nnc(NC(=O)Nc3ccc(C)c(Cl)c3)s1)cc2=O Show InChI InChI=1S/C20H17ClN6O2S2/c1-11-5-6-27-16(7-11)22-14(9-17(27)28)10-30-20-26-25-19(31-20)24-18(29)23-13-4-3-12(2)15(21)8-13/h3-9H,10H2,1-2H3,(H2,23,24,25,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	668	n/a	n/a	n/a	n/a	n/a	n/a
Zoetis Inc Curated by ChEMBL					Assay Description Inhibition of human full length TRKA expressed in CHO cells assessed as decrease in NGF-induced Ca2+ flux by Calcium 4 dye-based FLIPR TETRA assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126680 BindingDB Entry DOI: 10.7270/Q2280BVB
					More data for this Ligand-Target Pair