Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50505005'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50505005 (CHEMBL4455810) Show SMILES COCCOc1cc(ccc1Oc1ccccc1)-n1c(=O)[nH]c(=O)n(-c2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H20ClN3O6/c1-32-13-14-33-21-15-18(11-12-20(21)34-19-5-3-2-4-6-19)28-23(30)26-22(29)27(24(28)31)17-9-7-16(25)8-10-17/h2-12,15H,13-14H2,1H3,(H,26,29,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at TrkA (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NGF by fluorescence...				ACS Med Chem Lett 10: 1590-1591 (2019) Article DOI: 10.1021/acsmedchemlett.9b00506 BindingDB Entry DOI: 10.7270/Q2GM8BKZ
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