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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50528541'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50528541
PNG
(CHEMBL4437631)
Show SMILES CN([C@@H]1Cc2ccc(cc2C1)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1)c1cncnc1 |r|
Show InChI InChI=1S/C26H23F3N6O/c1-16-13-35(15-32-16)23-9-20(26(27,28)29)8-21(10-23)33-25(36)18-4-3-17-6-22(7-19(17)5-18)34(2)24-11-30-14-31-12-24/h3-5,8-15,22H,6-7H2,1-2H3,(H,33,36)/t22-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human TrkA expressed in baculovirus expression system using Tyr1 peptide as substrate after 1.5 hrs by FRET-based Z-LYTE ass...

J Med Chem 62: 7431-7444 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00365
BindingDB Entry DOI: 10.7270/Q2DZ0CSV
More data for this
Ligand-Target Pair