Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor [441-796]' and Ligand = 'BDBM227000'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227000 (US9328096, 688) Show SMILES COc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C29H22ClFN6O3/c1-40-27-13-18(10-12-33-27)17-34-29(39)25-16-26(37(36-25)19-7-3-2-4-8-19)35-28(38)20-14-21(23(31)15-22(20)30)24-9-5-6-11-32-24/h2-16H,17H2,1H3,(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.56	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
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