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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50146358'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50146358
PNG
(4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...)
Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C29H31NO/c1-2-8-21(9-3-1)22-14-16-30(17-15-22)20-25-19-28-26-12-6-4-10-23(26)18-24-11-5-7-13-27(24)29(28)31-25/h1-13,22,25,28-29H,14-20H2/t25?,28-,29-/m1/s1
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Similars
Article
PubMed
 30n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells

Bioorg Med Chem Lett 14: 2765-71 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.069
BindingDB Entry DOI: 10.7270/Q21835ZF
More data for this
Ligand-Target Pair