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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50418279'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50418279
PNG
(CHEMBL1767159)
Show SMILES Clc1ccc(Cc2nn(C3CCCN(Cc4ccc(OCCCN5CCCCCC5)cc4)CC3)c(=O)c3ccccc23)cc1
Show InChI InChI=1S/C37H45ClN4O2/c38-31-16-12-29(13-17-31)27-36-34-10-3-4-11-35(34)37(43)42(39-36)32-9-7-23-41(25-20-32)28-30-14-18-33(19-15-30)44-26-8-24-40-21-5-1-2-6-22-40/h3-4,10-19,32H,1-2,5-9,20-28H2
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Similars
Article
PubMed
 50.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...

J Med Chem 54: 2183-95 (2011)


Article DOI: 10.1021/jm1013874
BindingDB Entry DOI: 10.7270/Q2GQ6Z2Z
More data for this
Ligand-Target Pair