BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H2 receptor' and Ligand = 'BDBM50103506'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50103506 (Ranitidine \| Tritec \| Zantac) Show SMILES CNC(NCCSCc1ccc(CN(C)C)o1)=C[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Inhibition of [125I]APT binding to histamine H2 receptor in guinea pig cerebral membranes.				J Med Chem 35: 2231-8 (1992) BindingDB Entry DOI: 10.7270/Q23T9JFP
Freie Universit£t Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50103506 (Ranitidine \| Tritec \| Zantac) Show SMILES CNC(NCCSCc1ccc(CN(C)C)o1)=C[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars		n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Histamine H2 receptor antagonistic activity				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP773S
TBA					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50103506 (Ranitidine \| Tritec \| Zantac) Show SMILES CNC(NCCSCc1ccc(CN(C)C)o1)=C[N+]([O-])=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to histamine H2 receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-004-0012-z BindingDB Entry DOI: 10.7270/Q2ZG6W4Z
TBA					More data for this Ligand-Target Pair