Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108311 (US8604046, 91) Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)C3CCCCC3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C31H45FN4O2/c1-23-6-5-16-35(23)25-11-17-33(18-12-25)26-9-10-28(27(32)22-26)36-21-15-31(30(36)38)13-19-34(20-14-31)29(37)24-7-3-2-4-8-24/h9-10,22-25H,2-8,11-21H2,1H3/t23-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
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