Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM158358'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM158358 (US9029381, 10 | US9029381, 11 | US9029381, 12) Show SMILES CC(C)N1CCN(CC1)C(=O)[C@H]1CC1c1ccc(F)cc1 |r| Show InChI InChI=1S/C17H23FN2O/c1-12(2)19-7-9-20(10-8-19)17(21)16-11-15(16)13-3-5-14(18)6-4-13/h3-6,12,15-16H,7-11H2,1-2H3/t15?,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.63	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca AB US Patent					Assay Description The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...				US Patent US9029381 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BDG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM158358 (US9029381, 10 | US9029381, 11 | US9029381, 12) Show SMILES CC(C)N1CCN(CC1)C(=O)[C@H]1CC1c1ccc(F)cc1 |r| Show InChI InChI=1S/C17H23FN2O/c1-12(2)19-7-9-20(10-8-19)17(21)16-11-15(16)13-3-5-14(18)6-4-13/h3-6,12,15-16H,7-11H2,1-2H3/t15?,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca AB US Patent					Assay Description The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...				US Patent US9029381 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BDG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM158358 (US9029381, 10 | US9029381, 11 | US9029381, 12) Show SMILES CC(C)N1CCN(CC1)C(=O)[C@H]1CC1c1ccc(F)cc1 |r| Show InChI InChI=1S/C17H23FN2O/c1-12(2)19-7-9-20(10-8-19)17(21)16-11-15(16)13-3-5-14(18)6-4-13/h3-6,12,15-16H,7-11H2,1-2H3/t15?,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca AB US Patent					Assay Description The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...				US Patent US9029381 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BDG
					More data for this Ligand-Target Pair