Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM294456'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM294456 (US9586959, Compound 76) Show SMILES Clc1cnc2nc(N3CCN(CC3)C3CC3)c3nncn3c2c1 Show InChI InChI=1S/C15H16ClN7/c16-10-7-12-13(17-8-10)19-14(15-20-18-9-23(12)15)22-5-3-21(4-6-22)11-1-2-11/h7-9,11H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...				Citation and Details Article DOI: 10.1021/acs.jmedchem.7b01855 BindingDB Entry DOI: 10.7270/Q2ZG6WZQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM294456 (US9586959, Compound 76) Show SMILES Clc1cnc2nc(N3CCN(CC3)C3CC3)c3nncn3c2c1 Show InChI InChI=1S/C15H16ClN7/c16-10-7-12-13(17-8-10)19-14(15-20-18-9-23(12)15)22-5-3-21(4-6-22)11-1-2-11/h7-9,11H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+8	n/a	n/a	n/a	n/a	7.4	27
C&C RESEARCH LABORATORIES US Patent					Assay Description Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...				US Patent US9586959 (2017) BindingDB Entry DOI: 10.7270/Q2C53NWD
					More data for this Ligand-Target Pair