Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50139377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139377 (4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-be...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C21H20N2O/c22-15-16-3-5-17(6-4-16)18-7-8-21-19(13-18)14-20(24-21)9-12-23-10-1-2-11-23/h3-8,13-14H,1-2,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139377 (4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-be...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C21H20N2O/c22-15-16-3-5-17(6-4-16)18-7-8-21-19(13-18)14-20(24-21)9-12-23-10-1-2-11-23/h3-8,13-14H,1-2,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139377 (4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-be...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C21H20N2O/c22-15-16-3-5-17(6-4-16)18-7-8-21-19(13-18)14-20(24-21)9-12-23-10-1-2-11-23/h3-8,13-14H,1-2,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139377 (4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-be...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C21H20N2O/c22-15-16-3-5-17(6-4-16)18-7-8-21-19(13-18)14-20(24-21)9-12-23-10-1-2-11-23/h3-8,13-14H,1-2,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair