BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50222968'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50222968 (Cipralisant \| GT-2331) Show SMILES CC(C)(C)CCC#C[C@@H]1C[C@H]1c1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Binding affinity of compound against Histamine H3 receptor				J Med Chem 42: 1193-202 (1999) Article DOI: 10.1021/jm980408v BindingDB Entry DOI: 10.7270/Q20Z760D
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50222968 (Cipralisant \| GT-2331) Show SMILES CC(C)(C)CCC#C[C@@H]1C[C@H]1c1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards rat cortical H3 receptor				Bioorg Med Chem Lett 13: 1325-8 (2003) BindingDB Entry DOI: 10.7270/Q2HM59NM
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50222968 (Cipralisant \| GT-2331) Show SMILES CC(C)(C)CCC#C[C@@H]1C[C@H]1c1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for human recombinant H3 receptor				Bioorg Med Chem Lett 13: 1325-8 (2003) BindingDB Entry DOI: 10.7270/Q2HM59NM
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair